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Can Res 80(24):54355448 Wu H, Liu Q, Shan,X, Gao W, Chen Q (2023) ATM orchestrates ferritinophagy and ferroptosis by phosphorylating NCOA4
To assess the impact of FOXO4-DRI on endothelial cell senescence, the senescent endothelial cells were treated with FOXO4-DRI, followed by immunofluorescence and Western blotting experiments
Axonal myelination was analyzed according to the following quantifications: (a) the total number of myelinated axons per 10,000 m 2
Still, results should be carefully generalized to cases of background kidney dysfunction or when using drugs with narrow therapeutic index
Preliminary studies suggest it is well-tolerated, but long-term safety and potential neurologic impacts need further investigation